Abstract Introduction This study aimed to investigate the long-term prognostic effects of different alteplase doses on patients with acute ischemic stroke (AIS).Methods In this cohort study, we enrolled 501 patients with AIS treated with intravenous thrombolysis with alteplase, with the primary endpoint event of recurrence of ischemic stroke and th
Comprehensive models of learning disorders have to consider both isolated learning disorders that affect one learning domain only, as well as comorbidity between learning disorders.However, empirical evidence on comorbidity rates including all three learning disorders as defined by DSM-5 (deficits in reading, writing, and mathematics) is scarce.The
Introduction: Gout is a Electric Knife type of painful inflammation initiated by the interactions between monosodium urate crystals and connective tissue.Xanthine oxidase (XO) catalyzes the oxidation of hypoxanthine to xanthine, then to uric acid.The primary treatments for gout include XO inhibitors.At present, allopurinol is the most used XO inhib